Poster Presentation Clinical Oncology Society of Australia Annual Scientific Meeting 2019

A comparative study of physical activity levels and sedentary behavior patterns between disease stages of prostate cancer patients (#181)

Renée Bultijnck 1 2 , Noëmi Borrey 3 , Benedicte Deforche 4 5 , Elke Rammant 1 , Sofie Everaert 1 , Valérie Fonteyne 1 , Karel Decaestecker 1 , Nicolaas Lumen 1 , Piet Ost 1 2
  1. Department of Human Structure and Repair, Ghent University, Ghent, Belgium
  2. Research Foundation - Flanders (FWO), Brussels, Belgium
  3. Department of Physical and Rehabilitation Medicine, Ghent University Hospital, Ghent, Belgium
  4. Department of Public Health and Primary Care, Ghent University, Ghent, Belgium
  5. Department of Physical Activity, Nutrition and Health, Vrije Universiteit Brussel, Brussels, Belgium

Aim

To compare physical activity (PA) levels and sedentary behavior (SB) patterns between different disease stages in prostate cancer (PCa) (clinically localized disease versus clinical metastases disease).

Methods

A prospective cohort study in PCa patients across a wide range of disease stages was conducted. Inclusion criteria were; absence of psychological, familial, geographical or cognitive conditions which could hamper with the protocol, willingness to wear an activity tracker for 7 days and Karnofsky performance score >60. PA (by activPAL and Godin Leisure-time exercise questionnaire) and SB (by activPAL) was assessed. Physical performance was measured by the 400-m walk test and physical function by the EORTC QLQ-C30 questionnaire. Motivational readiness for PA was assessed according to the trans theoretical model of behavior change. The Mann-Whitney U test was used to compare results between groups. 

Results

In total, 71 patients were included (38 clinically localized disease and 33 clinical metastases disease). Patient characteristics were well balanced between groups (age, marital, educational and work status). The overall median (range) age at time of inclusion was 68 (54–81) years in the clinically localized group and 71 (52–84) years in the clinical metastases group. No significant differences were observed between groups for PA, SB and for meeting PA guidelines. In the clinically localized disease group, 24% reported sufficient exercise levels according to the PA guidelines and 12% in the clinical metastases disease. Both physical performance and function was worse (p<0.05) in the clinical metastases group (median 290s, ±84; 83±22) compared to the clinically localized group (median 281s ±33; 93 ±11). No significant differences were observed between groups for motivational readiness for PA.

Conclusion

PA levels were insufficient compared to the guidelines. Physical performance and function were worse in patients with more advanced disease stage. Therefore, disease stage adjusted interventions are required.