Oral Presentation Clinical Oncology Society of Australia Annual Scientific Meeting 2019

Nutrition and Exercise Interventions for Prostate Cancer (#16)

Brenton J Baguley 1
  1. School of Exercise and Nutrition Sciences , Deakin University, Melbourne, VIC, Australia

Obesity, poor diet quality and physical inactivity have been associated with an increased risk of prostate cancer-specific mortality, all cause-mortality, and treatment-related side effects for prostate cancer survivors. It is estimated that approximately 45% of all prostate cancer survivors are being treated with androgen deprivation therapy (ADT). However, ADT comes with significant side effects, including, but not limited to, unfavourable changes in body composition (reductions in muscle and bone mass, and increases in fat mass), and increased risks of cardiovascular disease, insulin resistance and metabolic syndrome. The dietary and exercise guidelines for cancer survivors suggest (a) to maintain a healthy body weight, (b) follow a dietary pattern high in fruit, vegetables and wholegrains, (c) and engage in at least 150 minutes/week of moderate-vigorous aerobic exercise, with 2-3 resistance training sessions/week of major muscle groups. Despite these guidelines, only a few diet interventions with/without exercise have been published in prostate cancer survivors, or men treated with ADT. Importantly, the utility of dietary interventions to improve disease- and treatment-related health outcomes in ADT are yet to be definitively explored. This presentation will discuss the current dietary patterns of Australian prostate cancer survivors, and describe a series of diet interventions with/without exercise in prostate cancer aiming to counteract the side effects of ADT.