Poster Presentation Clinical Oncology Society of Australia Annual Scientific Meeting 2019

A Victorian clinician-based survey on current practices for breast cancer staging in pregnancy (#322)

Harriet Herbison 1 , Abigail Miller 1 , Christopher D Hart 2 , Theresa Hayes 3 , Darryl Shnier 4 , Josephine Stewart 5 , Lee Na Teo 6 , Jacqui Thomson 7 , Javier Torres 8 , Sally Greenberg 9 , Bianca Devitt 1
  1. Oncology Department, Eastern Health, Box Hill, VIC , Australia
  2. Oncology Department, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia
  3. Oncology Department, South West Healthcare, Warnambool, VIC, Australia
  4. Radiology Department, Western Health, St Albans, VIC, Australia
  5. Oncology Department, Austin Health, Heidelberg, VIC, Australia
  6. Oncology Department, Ballarat Health Services, Ballarat, VIC, Australia
  7. Oncology Department, Peninsula Health, Frankston, VIC , Australia
  8. Oncology Department, Goulburn Valley Health, Shepparton, VIC, Australia
  9. Oncology Department, Western Health, VIC, Australia

Background/aims: Incidence of cancer during pregnancy is rising.1 There is limited evidence, and no national guidelines regarding when to perform staging and which imaging modalities are safe and accurate during pregnancy. This study assesses current Victorian clinician practices for staging of pregnant women with breast cancer.

Methods: A study specific survey was administered to medical oncologists, surgeons, radiation oncologists, radiologists and specialty trainees at breast multidisciplinary meetings across regional and metropolitan Victoria. The questionnaire assessed clinician level of work experience, perceived indications for staging, and preferred imaging modalities in breast cancer patients who are pregnant.

Results: 103 questionnaires were completed with an overall response rate of 87%. 87 cancer specialists (35 surgeons, 33 medical oncologists, 12 radiologists, 7 radiation oncologists) and 16 trainees completed the survey. 76(74%) of clinicians had worked in their field for > 6 years and 65(63%) had treated at least one pregnant woman with breast cancer. 2% of clinicians would not stage during pregnancy. 61(59%) would stage in locally advanced or inflammatory, 56(54%) in clinical node involvement, 79(77%) if strongly suspicious of metastatic disease. 50% and 59% of clinicians would order chest x-ray and liver ultrasound respectively. Less frequently selected tests included CT chest (11%), whole spine MRI (8%), whole body MRI (8%), whole body bone scan (5%), and CT abdomen and pelvis (1%). 87% of clinicians would like local or national guidelines in this area. 

Conclusions: There is variability in clinical practice for staging pregnant women with breast cancer. The majority of clinicians surveyed believe guidelines are warranted. We plan to develop consensus guidelines on the use of imaging for staging of pregnant women with breast cancer.

  1. Lee, Y. , Roberts, C. , Dobbins, T. , Stavrou, E. , Black, K. , Morris, J. and Young, J. (2012), Incidence and outcomes of pregnancy‐associated cancer in Australia, 1994–2008: a population‐based linkage study. BJOG: An International Journal of Obstetrics & Gynaecology, 119: 1572-1582. doi:10.1111/j.1471-0528.2012.03475.x